The practice of Prosthodontics plays a pivotal role in enhancing the quality of life for patients suffering from debilitating conditions, particularly those affected by wasting diseases of the oral cavity. These conditions, which often lead to the loss of vital structures such as teeth, bone, and soft tissues, pose unique challenges for both diagnosis and treatment. The significance of providing restorative care to these patients cannot be overstated, as effective prosthodontic rehabilitation can restore functionality, aesthetics, and confidence. This book, Prosthodontic Rehabilitation in Wasting Diseases of the Oral Cavity, is a comprehensive guide that bridges the gap between clinical expertise and the specific needs of patients with oral wasting diseases. It presents a detailed exploration of the challenges involved in prosthodontic treatment for this patient population, offering a structured approach to both diagnosis and therapy. Written by Dr. Manhit Singh Lehl and Dr. Saloni, this work draws upon years of clinical experience and research in the field of Prosthodontics. The chapters provide insight into the intricacies of patient management, focusing on the rehabilitation of those whose oral structures have been severely compromised. Special emphasis is placed on the diagnostic techniques, treatment planning strategies, and innovative prosthodontic solutions that can restore both function and aesthetics for these patients. Our aim is to provide an invaluable resource for dental professionals, enabling them to approach the complexities of prosthodontic rehabilitation with confidence and precision. We hope this book serves as a guide to furthering knowledge in this important area of dental care, with the ultimate goal of improving the lives of patients affected by wasting diseases of the oral cavity.