One major objective of writing this book is to update information and simplify the small yet complex cytoskeletal protein knows as cytokeratins so that it is more easily understood and assimilated by the reader. Although the scope of the textbook remains structure, form, function and classification of cytokeratin, antibodies and its presentation in various health and disease conditions have been integrated in areas where they are essential. Illustrations and figures are added in colour to facilitate visualization of the subject matter.Knowledge of form, function and structure, molecular organization is essential to understand the normal cell biology and phenomenon as well as pathogenesis of various diseases at the cellular level. The textbook is intended to serve as a learning guide for students. The book provides an overview of the subject matter covered. Although coverage is exhaustive, the text has been structured with the focus on learning and understanding concepts. Undergraduate and postgraduate students will find a degree of coverage suited for their respective needs. While every effort has been made to keep the text error free a few may still be slip through. I would be grateful if teachers and students write to me if they find any.