This book is an abridged version of thesis on gastrointestinal lesions in Western Uttar Pradesh which was undertaken at Jawaharlal Nehru Medical college, Aligarh Muslim University. This book intends to enlighten graduates, postgraduates in field of Surgery and Pathology with the subspeciality of Surgical pathology and specifically Gastrointestinal pathology. This book also contains necessary know how on Immunohistochemistry and it's role in Gastrointestinal tumors thereby providing important information on oncopathology. This book may serve as a mini-atlas on gastrointestinal lesions and provide as guide for research activities.